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Research Associate I/II - Molecular Biology

Position Summary:

We seek a highly motivated and diligent molecular biologist to join the Therapeutic Antibodies group at Achaogen.  The successful candidate will operate in a highly diverse and dynamic research environment and contribute to the advancement of drug discovery projects in disease areas with high unmet medical need. This role will be responsible for high throughput RT-PCR utilizing liquid handling robotics, cDNA sequencing and vector construction, amongst other activities.  Attention to detail, the ability to communicate across multiple scientific disciplines and a persistent drive for results are critical to the role. 

Key Attributes:


  • Intense drive to make progress on impactful research programs
  • Excellent communicator with ability to clearly present results and recommendations
  • Exceptional troubleshooting skills
  • Ability to work in a fast-paced environment focused on maximizing throughput with optimal quality

Essential Functions:


  • Perform molecular lab techniques including RT-PCR, electrophoresis, enzymatic assays, protein/DNA quantitation, bacterial cell culture, molecular cloning & primer design
  • Utilize Achaogen’s automated liquid handlers to efficiently amplify and clone IgG encoding sequences from individual B cells
  • Generate antibody expression constructs for sequencing and transient transfection of mammalian cells
  • Develop creative strategies to streamline and optimize workflow of existing methods to advance research programs
  • Maintain diligent records and prepare/deliver presentations on technical progress.
  • Work seamlessly in an energetic, interdisciplinary environment encompassing molecular biology, protein expression, and microfluidics.


Essential Experience:

  • 1+ year of experience in an academic or industrial laboratory
  • Proficient in standard molecular biology techniques (e.g. PCR and product purification, cloning and plasmid construction, plasmid purification, gel electrophoresis, etc.)
  • Hands-on experience in mRNA extraction and conversation to cDNA for downstream cloning

Preferred Experience:

  • Experience with operating and programming automated liquid handling robotics
  • Experience with modern cloning techniques such as Gibson Isothermal Assembly and Type IIs cloning
  • Demonstrated success in a dynamic research environment where adaptability to new projects and approaches was essential
  • Experience with microbial recombineering techniques, including lambda red knockout generation and P1 phage transductions


  • Minimum of a BS or MS degree in a relevant scientific field (e.g. molecular & cellular biology, biochemistry or biological/chemical engineering)


  • Exceptional written and verbal communication skills
  • Excellent organization skills
  • Committed to the values of integrity, accountability, transparency, scientific rigor and drive
  • Current US work authorization required
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