Achaogen is seeking a Computational Chemist to join our multidisciplinary research team. The successful candidate will support small and large molecule project teams through target identification, hit discovery, and lead optimization. It is expected that the successful candidate will have a proven track record of collaborative teamwork to solve challenging scientific issues. A qualified candidate will be entrepreneurial, detail-oriented, well-networked, and be able to flexibly apply computational methods to a wide range of scientific problem solving.
For small molecule drug discovery, collaborative work with medicinal chemists and project teams to identify novel chemistry starting points and design compounds with improved potency, selectivity, functional activity and/or ADME properties will be a core work function. In addition, the work will include coaching scientists and non-scientists to analyze, interpret, and visualize biological data, and communication these results. Working with the head of chemistry the role holder will build an in-house and networked computational chemistry infrastructure being solely accountable for devising, championing or developing state of the art computational chemistry techniques that solve key problems for project and chemistry teams.
In addition, Achaogen also undertakes large molecule drug discovery and the candidate will be expected to contribute to ongoing research efforts in collaboration with internal scientists.
Additionally, the role holder may take on the chemistry and / or project leadership of drug discovery teams.