View Our Website View All Jobs

Senior Director / VP, Head of Clinical Pharmacology, DMPK & Bioanalytical

Position Summary:

Achaogen is a clinical-stage biopharmaceutical company passionately committed to the discovery, development, and commercialization of innovative antibacterials to treat multi-drug resistant, Gram-negative infections. In light of recent positive Phase 3 data for our NDA-candidate with breakthrough therapy designation, plazomicin, and a growing pipeline that includes two small molecules in early development and multiple large and small molecule discovery programs, we are looking for an accomplished scientist to lead our growing clinical pharmacology, DMPK and bioanalytical groups.


We seek a highly motivated and driven scientist with proven leadership abilities. This position will provide an exciting opportunity to lead an experienced clinical pharmacology team as they file the NDA and MAA for plazomicin, advance early development programs through IND to clinical proof of concept, and partner with the research group as they look to translate their work into the clinic. If you are passionate about science, are strategically agile, like working in a team, are looking to grow in your career and are committed to performing rigorous experiments that inform drug development, then this is the place for you!



  • Ultimately accountable for the scientific output, conduct and resourcing of the clinical pharmacology, DMPK and bioanalytical functions.
  • Build and lead a clinical pharmacology, DMPK and bioanalytical groups, growing the team’s existing high level of scientific excellence to global recognition as the #1 clinical pharmacology group in terms of drug development for areas of critical unmet need, academic accomplishment and camaraderie.
  • Take an active role and pride in developing scientists both within the clinical pharmacology / DMPK function and across the business, helping them grow their careers and step up to fill critical business needs.
  • Leverage prior experience with regulatory agencies and on cross-functional development teams to help the function set appropriate strategy for dose justification, clinical pharmacology plans, and regulatory filings.
  • Represent the clinical pharmacology and DMPK functions as a standing reviewer on Achaogen’s scientific and development review committees, providing technical guidance to individual programs, endorsement of resource plans and portfolio prioritization.
  • Lead by example in maintaining the effective partnerships between clinical pharmacology, DMPK and related functions in research and development.
  • Manage the clinical pharmacology, DMPK and bioanalytical functions including responsibility for budget and hiring.
  • Collaborate with vendors, consultants and collaborators to accomplish goals and deliverables of the department.
  • Present operational plans, scientific data and strategy to internal and external audiences, including regulators, key opinion leaders, partners and executives.
  • Review relevant reports and other scientific data for regulatory filings.
  • Participate in in-licensing and out-licensing activities.


Essential Experience:

  • 10 or more years of relevant industry experience in clinical pharmacology, pharmacometrics, DMPK or related discipline(s), including experience with small molecules and antibody therapeutics.
  • 5 or more years of management experience including at least 2 years leading a clinical pharmacology department.
  • Proven track record with regulatory deliverables and interactions, including IND filings and significant contributions to small molecule NDA/MAA filings.
  • Record of scientific excellence, including publications in top tier journals.


Preferred Experience:

  • Experience with anti-bacterial and/or anti-infective drug development.



  • PharmD or PhD in pharmacokinetics, pharmacometrics, clinical pharmacology or a related field.


Preferred Additional Skills:

  • Motivated and passionate about making a difference for unmet medical needs.
  • Strong oral and written communication skills and business partnering ability.
  • Strong interpersonal skills and ability to work with others in a positive, collaborative manner, inspiring trust and confidence with colleagues.
  • Willingness to be a “hands-on, roll-up-your sleeves” leader.
  • Committed to values of integrity, accountability, transparency, scientific rigor and drive.
  • Current US work authorization required.
  • Ability to travel domestically and internationally.
Read More

Apply for this position

Apply with Indeed
Attach resume as .pdf, .doc, or .docx (limit 2MB) or Paste resume

Paste your resume here or Attach resume file

To comply with government Equal Employment Opportunity / Affirmative Action reporting regulations, we are requesting (but NOT requiring) that you enter this personal data. This information will not be used in connection with any employment decisions, and will be used solely as permitted by state and federal law. Your voluntary cooperation would be appreciated. Learn more.

Invitation for Job Applicants to Self-Identify as a U.S. Veteran
  • A “disabled veteran” is one of the following:
    • a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or
    • a person who was discharged or released from active duty because of a service-connected disability.
  • A “recently separated veteran” means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
  • An “active duty wartime or campaign badge veteran” means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
  • An “Armed forces service medal veteran” means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
Veteran status

Voluntary Self-Identification of Disability
Voluntary Self-Identification of Disability Form CC-305
OMB Control Number 1250-0005
Expires 1/31/2020
Why are you being asked to complete this form?

Because we do business with the government, we must reach out to, hire, and provide equal opportunity to qualified people with disabilities.i To help us measure how well we are doing, we are asking you to tell us if you have a disability or if you ever had a disability. Completing this form is voluntary, but we hope that you will choose to fill it out. If you are applying for a job, any answer you give will be kept private and will not be used against you in any way.

If you already work for us, your answer will not be used against you in any way. Because a person may become disabled at any time, we are required to ask all of our employees to update their information every five years. You may voluntarily self-identify as having a disability on this form without fear of any punishment because you did not identify as having a disability earlier.

How do I know if I have a disability?

You are considered to have a disability if you have a physical or mental impairment or medical condition that substantially limits a major life activity, or if you have a history or record of such an impairment or medical condition.

Disabilities include, but are not limited to:

  • Blindness
  • Deafness
  • Cancer
  • Diabetes
  • Epilepsy
  • Autism
  • Cerebral palsy
  • Schizophrenia
  • Muscular dystrophy
  • Bipolar disorder
  • Major depression
  • Multiple sclerosis (MS)
  • Missing limbs or partially missing limbs
  • Post-traumatic stress disorder (PTSD)
  • Obsessive compulsive disorder
  • Impairments requiring the use of a wheelchair
  • Intellectual disability (previously called mental retardation)
Please check one of the boxes below:

You must enter your name and date
Your Name Today's Date
Reasonable Accommodation Notice

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

iSection 503 of the Rehabilitation Act of 1973, as amended. For more information about this form or the equal employment obligations of Federal contractors, visit the U.S. Department of Labor's Office of Federal Contract Compliance Programs (OFCCP) website at

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.