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Principal Scientist, Chemistry

Position Summary:

Achaogen is seeking a proactive, highly motivated, organized and collaborative Principal Scientists to join our dynamic team of Medicinal Chemists seeking to develop new cures for multi-drug resistant bacterial infections.

The Principal Scientist will have a leading role in all the activities of the chemistry group focusing on scientific excellence in the research, evaluation, and development of novel drug targets and drug candidates to treat serious bacterial infections and other unmet medical needs as required. The Principal Scientist will develop strategies to ensure effective achievement of scientific objectives in collaboration with cross-functional partners. It is expected that the role will include personal contributions in the laboratory, collaboration with others on the principles and theories or drug design and synthesis, and the scientific development of personnel, primarily but not exclusively within chemistry, to ensure the efficient operation of the research function. Additionally, the Principal Scientist will be expected to write and review manuscripts for publication, present at scientific conferences, and develop a significant external presence to represent Achaogen science.  


Essential Functions:

  • Works on abstract problems within functional areas of the business.
  • Identifies and evaluates fundamental problems for major functional areas through assessment of intangible variables.
  • Interacts internally and externally with key opinion leaders requiring negotiation of difficult matters to influence scientific and technical direction of the company.
  • Directs and controls the activities of one or more functional areas in collaboration with managers with overall responsibility for the direction of those assigned areas.
  • High-level participation in project planning & departmental budgeting.
  • Is contributing to the design, development, and implementation of programs.
  • Conducts and collaborates with others on basic research and development relevant to long-term objectives.
  • Develops strategies to ensure effective achievement of objectives. 


Preferred Experience:

  • 15+ years of work experience in a research and/or development environment is preferred.
  • Previous management or project planning experience is required.


Preferred Education:

  • B.S./B.A. or M.S./M.A. in a scientific discipline with 15+ years’ work experience. 
  • PhD in a chemistry related discipline with 10+ years’ experience is preferred.

Additional Skills:

  • Proficient with relevant chemistry related IT packages.
  • Demonstrated consistency in professional and effective management style.
  • Consistent successful completion or resolution of major projects.
  • Demonstrated excellence in independent management of complex projects.
  • Demonstrated leadership in business/strategic thinking and commercial/industry understanding for own and peer projects.
  • Has proven consistent leadership qualities in technical proficiency, scientific creativity, collaborations with others and independent thought.
  • Internal and external accepted thought leader in relevant area(s) of expertise.
  • Committed to the values of integrity, accountability, transparency, scientific rigor and drive.
  • Current US work authorization required.
  • Ability to travel domestically and internationally.
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