The aminoglycoside class antibiotic drugs present significant intellectual and practical challenges especially with respect to their preparation which limits our ability to identify, characterize, and optimize new candidates. To address this, we aim to develop a wide-range of novel synthetic chemistry routes and procedures to aid in the diverse production of novel aminoglycosides both at milligram and multigram scales.
We are seeking a highly motivated Postdoctoral Research Fellow to join our Medicinal Chemistry group and engage in novel synthetic chemistry research. The proposed research project will involve the elucidation of novel synthetic chemistry, novel synthetic routes, and the development of innovative chemical systems such as flow chemistry, to enable access to novel aminoglycosides.
The Achaogen postdoctoral program is an immersive three-year opportunity designed to enable highly independent and motivated scientists to perform impactful basic or translational research in a biotech-industry setting. Fellows will be paired with an internal scientific mentor and integrate into in a highly interdisciplinary environment, surrounded by high-caliber researchers with diverse scientific backgrounds. We strive to empower Achaogen postdocs to make influential discoveries that result in high-impact publications and contribute to the overall goal of developing new medicines to treat drug-resistant bacterial infections.
Preferred Additional Skills: